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CAMBRIDGE, MASS. — AVEO Pharmaceuticals Inc. has signed a new, 12-year lease for 126,000 square feet of laboratory and office space at 650 Kendall St. in Cambridge. AVEO, a cancer therapeutics company, plans to use the six-story facility for its headquarters. A joint venture between BioMed Realty and Prudential Real Estate Investors owns 650 E. Kendall St., which is comprised of a 280,000-square-foot research facility.