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NEW YORK CITY — Law firm Akerman LLP has signed a 100,000-square-foot office lease at 1251 Avenue of the Americas in Manhattan. Akerman will move from its current office at 666 Fifth Avenue to the entire 37th and 38th floors and a portion of the 35th floor at the new building. About 185 lawyers will work out of the new space. Other tenants of the building include MUFG Union Bank, Trust Co. of the West and Mizuho Corporate Bank. Matthew Cheezem, Ken Siegel and Lisa Kiell of JLL represented Akerman in the lease negotiations. David Falk and Peter Shimkin of Newmark Knight Frank represented the landlord, Mitsui Fudosan America Inc., the U.S. subsidiary of Japanese real estate company Mitsui Fudosan Co. Ltd.