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NEW HAVEN, CONN. — Alexion Pharmaceuticals Inc. has broken ground on 100 College Street, a state-of-the-art laboratory and office building that will house the company’s new global headquarters in New Haven’s Downtown Crossing neighborhood. Alexion will be the anchor tenant in 100 College Street, occupying nine floors. The building is expected to be open for occupancy in 2015. Alexion plans to relocate more than 400 employees who are currently based in Connecticut to the new site in 2015. The state-of-the-art, 11-story office building is the first building to be erected as part of New Haven’s Downtown Crossing urban revitalization effort. The building is being constructed to be certifiable of at least LEED Silver.