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LOS ANGELES — Federal Public Defenders Office has signed a 10-year lease for 50,130 square feet of office space in the Little Tokyo Historic District of downtown Los Angeles. The space is located at 321 E. 2nd St. The property was built in 1963. GSA represented the tenant. John Anthony, Chris Steck and Chris Giordano of Charles Dunn Co. represented the landlord, 321 E. Little Tokyo Master LLC.