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CAMBRIDGE, MASS. — Ironwood Pharmaceuticals has expanded its lease at 301 Binney Street, a five-story laboratory research facility located at Kendall Square in Cambridge. The company is leasing an additional 50,000 square feet, bringing its total space occupied at the property to approximately 164,000 square feet. The property is owned by BioMed Realty Trust through a joint venture with a client of Prudential Real Estate Investors.