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HOLDEN, MASS. — Construction crews have broken ground on a three-story, 36,000-square-foot medical office building in Holden. Oriol Health Care, a family-owned healthcare organization, and Reliant Medical Group, a multi-specialty medical group, will occupy the space. The property will be located on the site of the former Holden District Hospital on Boyden Road. Reliant Medical Group will take 17,000 square feet in the building and offer a family medical practice, laboratory, pharmacy, radiology, OB/GYN services and an optical center. Cutler Associates is constructing the property, which is expected to be complete by the spring of 2013. Margulies Perruzi Architects designed the building.